Ijenereyitha yeNitrojeni eKhethekileyo yokuFaka isicelo kuShishino loShishino

Izixhobo ze-nitrogen zamachiza (ubunyulu be-nitrogen 99.99%) yijenereyitha ye-nitrogen yamayeza ephuhliswe ngokusekelwe kumava ophando lobungcali kunye nophuhliso loxinzelelo lwe-adsorption nitrogen generators kwiminyaka yakutshanje, ngokuhambelana nemigangatho ye-GMP. Xa kuthelekiswa nentsimbi cylinder nitrogen (okanye ulwelo nitrogen), ineendleko zokusebenza eziphantsi, ukucoceka nitrogen ezinzile, kunye nokusebenza lula.

Iinaliti zamanzi (ezifana ne-penicillin) kunye nezisombululo ezinkulu ze-infusion (ezifana ne-amino acids) ezihlala zixhomekeke kwi-oxidation kufuneka zizaliswe nge-nitrogen ukuze zikhuseleke, ngaphandle koko isisombululo seyeza sifakwe i-oxidized ngexesha lokugcinwa, kubangela ukuwohloka. Ngokuqhelekileyo, ngaphambi kokupakishwa, indlela yokuzaliswa kwe-nitrogen isetyenziswa (okanye i-nitrogen enye yokugungxula) ukunciphisa ukuxinwa kwe-oksijini kwii-ampoules okanye iibhotile zokufakela ngaphantsi kwe-0.5%, okuvumela ukuba iyeza ligcinwe ixesha elide. Okwangoku, izixhobo ezithengiweyo ngabavelisi abaqhelekileyo malunga ne-5-20m3 / h, kunye nokuhlambuluka kwe-99.99%. Umahluko phakathi kwejenereyitha ye-nitrogen yamayeza kunye nezinye izixhobo ze-nitrogen kukuba ngokomgangatho wamazwe ngamazwe we-GMP kwishishini lamachiza, iinxalenye ezinxibelelana namachiza okanye amayeza angamalwelo zenziwe ngentsimbi engenasici kwaye zifuna inzala. Isixhobo kufuneka senziwe ngensimbi engenasici kwaye isixhobo sokucoca inzalo kufuneka sifakwe kwindawo yokukhupha initrogen yesixhobo. Kwakhona, ngenxa yokuba iifektri zamayeza zineemfuno eziphezulu ezipheleleyo zezixhobo, zihlala zikhetha ulungelelwaniso oluphezulu.

Kwizityalo ezenza izinto ezikrwada, igesi yenitrogen nayo iyafuneka kukhuseleko lwasemoyeni, kwaye inkqubo yokusebenzisa igesi yenitrogen ifana kakhulu naleyo yezityalo zemichiza emihle. Ukucoceka okuqhelekileyo yi-99% -99.9%, kodwa imali esetyenzisiweyo iyahluka ngokuxhomekeke kubukhulu befektri, kodwa inkulu kakhulu xa kuthelekiswa nemali esetyenziswa kwiijenereyitha ze-nitrogen zamachiza.

Xa umoya kuxinzelelo ngokucoca kunye nokomisa, iSiseko kwi-Aerodynamics, i-nitrogen kunye ne-oksijini emoyeni kwi-zeolite molecular sieve (ZMS) kwi-Pressure swing adsorption iya kusebenza kwezinga lokusasazwa okwahlukileyo ngokufaka i-nitrogen. Ioksijini ekwisihluzo semolekyuli yekhabhoni kumphezulu womlinganiselo wokusasazwa iphezulu kunenitrogen. Xa i-adsorption yayingekho kwi-balance, i-oksijeni yaxutywa yi-carbon molecular sieve ngobuninzi, kwaye i-nitrogen yayigxininiswe kwaye iphuculwe kwisigaba segesi ukufezekisa ukuhlukana kwe-oksijini kunye ne-nitrogen.